Karl Fischer titration is a classic titration method in analytical chemistry that uses coulometric or volumetric titration to determine trace amounts of water in a sample. There are many types of titrations with different procedures and objectives. The most common types of qualitative titration are acid-base titration and redox titration. Depending on the desired endpoint, a drop or less of a titrant can make the difference between a permanent and a temporary change in the indicator. When the end point of the reaction is reached, the volume of reactant consumed is measured and used to calculate the concentration of the analyte.